Illuminating Innovation: Deep-Sea Fish Inspire Breakthrough in Light-Driven Molecular MachineryGenerated with AI.
An international team of chemists, led by the Weizmann Institute and Tampere University, alongside Polish and UK collaborators, has made a groundbreaking advance in supramolecular chemistry, inspired by the visual systems of deep-sea fish. Their innovative approach transforms photoswitchable molecules like azobenzenes from stable to metastable states using low-energy red light, offering immense potential for applications in energy storage, light-activated drug delivery, and sensing technologies.
The researchers drew inspiration from the complex visual systems evolved in deep-sea fish, which use antenna-like molecules to absorb scarce photons in the red wavelength range. This absorption triggers a change in the retinal molecule, a process mimicking the transformation of cis-retinal to trans-retinal in nature, essential for visual perception.
Applying this natural mechanism, the team developed a novel supramolecular machine. It consists of a metal–organic cage housing an azobenzene molecule and a light-absorbing sensitizer. This setup allows for efficient conversion of azobenzenes from their stable form to a metastable one using visible light, a process previously limited by the need for UV light. This breakthrough enables the use of low-energy light in various applications, overcoming previous limitations in fields like photocatalysis and photopharmacology.
Significant research from Tampere University has revealed that these photochemical processes occur at astonishing speeds, in the nanosecond range, showcasing the efficiency of this new approach. The simplicity of this method, requiring just a mixture of components and light matching the sensitizer's absorption profile, underscores its practical applicability.
Looking ahead, this research opens new horizons in soft robotics and light-activated drug delivery systems. The team, buoyed by this success, is already venturing into developing the next generation of light-driven supramolecular machines, translating years of natural evolution into synthetic materials advancements in a fraction of the time.
This breakthrough exemplifies how nature's designs can inspire revolutionary advancements in science and technology. By mimicking the sophisticated visual system of deep-sea fish, researchers have unlocked new possibilities in molecular manipulation, setting the stage for innovative applications in diverse fields, from smart materials to healthcare. This fusion of natural inspiration and cutting-edge science heralds a new era of sustainable and efficient technological solutions.